QC FYI: HIV Began Decades Earlier Than Thought

The most pervasive global strain of HIV began spreading in humans around 1900 in sub-Saharan Africa, a new study claims. The research (published in the current issue of Nature), found that HIV began spreading between 1884 and 1924, around the same time urban centers in west central Africa were established. This estimated time of origin is decades earlier than the previous estimate of 1930.
The researchers worked with a 1960 sample of HIV gene fragments from a wax-embedded lymph-node tissue biopsy from a woman in Kinshasa in the Democratic Republic of the Congo. This 1960 virus is the second-oldest known HIV-1 group M genetic sequence, with the oldest being a 1959 blood sample from a man also from Kinshasa.
Worobey said that the HIV epidemic that resulted from the turn-of-the-century spread correlates to the urbanization of colonial Africa, principally the present-day city of Kinshasa in the Democratic Republic of the Congo. The growth of cities and associated high-risk behaviors may have been a principal cause of the rapid spread of the virus.
Lead researcher Michael Worobey, an assistant professor of ecology and evolutionary biology at the University of Arizona in Tucson, is optimistic about the eventual extinction of the HIV virus. “I think the picture that has emerged here, where changes the human population experienced may have opened the door to the spread of HIV, is a good reminder that we can make changes now that could help reverse the epidemic. If HIV has one weak spot, it is that it is a relatively poorly transmitted virus. From better testing and prevention, to wider use of the antiretroviral drug therapy, there are a number of ways to reduce transmission and force this virus back into extinction,” he said.
Read the full news article.